Glial Cell Line-Derived Neurotrophic Factor in the Vitreous of Patients With Proliferative Diabetic Retinopathy

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OBSERVATIONS Glial Cell Line–Derived Neurotrophic Factor in the Vitreous of Patients With Proliferative Diabetic Retinopathy

G lial cell line–derived neurotrophic factor (GDNF) belongs to the neurotrophic factor family. GDNF functions are not restricted to neurons but are also implicated in glial cell development (1). We observed high expression levels of GDNF receptor family -component 2 (GFR 2) in epiretinal membranes (ERMs) in proliferative diabetic retinopathy (PDR), indicating the involvement of GFR 2 in ERM for...

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Glial cell line-derived neurotrophic factor in the vitreous of patients with proliferative diabetic retinopathy.

G lial cell line–derived neurotrophic factor (GDNF) belongs to the neurotrophic factor family. GDNF functions are not restricted to neurons but are also implicated in glial cell development (1). We observed high expression levels of GDNF receptor family -component 2 (GFR 2) in epiretinal membranes (ERMs) in proliferative diabetic retinopathy (PDR), indicating the involvement of GFR 2 in ERM for...

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The Effects of Progesterone on Glial Cell Line-derived Neurotrophic Factor Secretion from C6 Glioma Cells

Objective(s)Progesterone is a steroid hormone whose biology has been greatly studied within the confines of reproductive function. In recent years, the neuroprotective effects of progesterone have attracted growing interest. Glial cell line-derived neurotrophic factor (GDNF), is a neurotrophic factor which plays a crucial role in the development and maintenance of distinct sets of central and p...

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increased expression of glial cell line-derived neurotrophic factor in rat brain after traumatic brain injury

glial cell line-derived neurotrophic factor (gdnf) plays important roles not only for the differentiation of neurons during normal development but also for the survival and recovery of many populations of mature neurons. the effect of traumatic brain injury (tbi) on the expression of gdnf is currently unknown. to determine if there is alteration in gdnf after tbi we examined the effect of contr...

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the effects of progesterone on glial cell line-derived neurotrophic factor secretion from c6 glioma cells

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ژورنال

عنوان ژورنال: Diabetes Care

سال: 2005

ISSN: 0149-5992,1935-5548

DOI: 10.2337/diacare.28.10.2588